Some results show that, in addition to the effect in normal hemostasis, TF plays an important role in cerebral thrombosis, atherosclerosis, acute coronary syndrome, deep vein thrombosis, disseminated intravascular coagulation, inflammation and tumor. 研究表明,TF除了在正常止血方面的作用外,其异常表达与脑血栓、动脉粥样硬化、急性冠脉综合症、深静脉血栓、弥散性血管内凝血、炎症及肿瘤等密切相关,日益受到广泛关注。